… of apixaban in comparison with warfarin were similar across different levels of centers’ and
patients’ predicted … and at least one risk factor for stroke. Participants were randomized to …

… to the trials of dabigatran, 20 apixaban, 21 and edoxaban. ROCKET-AF had … level comparisons
showed that DOACs had greater margins of efficacy and safety at sites with high control …

… , stroke, bleeding history, labile international normalized ratio, … also predict a higher bleeding
risk in patients taking warfarin, … a larger variability in international normalized ratio control. …

… efficacy and safety of NOACs for stroke prevention in patients with AF randomized to apixaban
versus warfarin … (n=9081) with a target international normalized ratio of 2.0 to 3.0. Patients …

… to poor quality of international normalized ratio control, which … be different from patients
who continued using warfarin in other … across the range of predicted quality of INR control [38]. …

… regular international normalized ratio testing and has frequent interactions with multiple drugs
and … , and CHA2DS2-VASc risk scores predicting stroke in patients with atrial fibrillation,” …

… ) for the prevention of stroke in nonvalvular atrial fibrillation (AF… 7 HAS-BLED score—International
Normalized Ratio (INR), 8 a … HAS-BLED score is a validated prediction measure for the …

… where apixaban was superior to warfarin both in stroke prevention … the international normalized
ratio (INR) during the study was 64%. … . Evidence that D-dimer levels predict subsequent …

… treatment to predict the absolute 1-year risks of outcome 22. … compared with warfarin, but
other observational studies have … weight, haemoglobin, international normalized ratio, serum …

… normalized ratio (INR) control. To determine the … In conclusion, regardless of the degree
of INR control, DOAC agents are preferable over warfarin as stroke prevention therapy for …